Clinical trial analysis of 2019-nCoV therapy registered in China.
Identifieur interne : 000822 ( Main/Exploration ); précédent : 000821; suivant : 000823Clinical trial analysis of 2019-nCoV therapy registered in China.
Auteurs : Qi Zhang [République populaire de Chine] ; Yakun Wang [République populaire de Chine] ; Changsong Qi [République populaire de Chine] ; Lin Shen [République populaire de Chine] ; Jian Li [République populaire de Chine]Source :
- Journal of medical virology [ 1096-9071 ] ; 2020.
Abstract
So far, there is a lack of effective drugs for the new coronavirus pneumonia. With more and more patients diagnosed, China has carried out more than 100 clinical studies of new coronavirus infection, including antiviral drugs, antimalarial drugs, glucocorticoids, plasma therapy, virus vaccine, and other Western drugs, while Chinese medicine research accounted for half of the studies. Most of the trials were initiated by investigators and the study period would last for 1 to 11 months. The primary endpoints included symptom improvement and virus nucleic acid turning negative, but the optimal endpoint has not been determined. Although the final results of studies will take a long time to complete, the interim research data may provide some help for the current urgent demand for drug treatment. Compared with that of during SARS period in 2003, China has the stronger capability to carry out clinical trials of new drugs in emergency period.
DOI: 10.1002/jmv.25733
PubMed: 32108352
Affiliations:
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effective drugs for the new coronavirus pneumonia. 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